Fen-Phen,
Pondimin & Redux
Clinical
studies have decisively proven the relationship between Pondimin,
Fen Phen and Redux and primary pulmonary hypertension
•
Pondimin is the brand name for Fenfluramine
• Redux is the brand name for Dexfenfluramine
• Pondimin combined with Redux, with the addition of Phentermine,
makes up the drug Fen-Phen.
Pondimin,
Redux and Fen-Phen were three of the most
widely prescribed diet drugs in the U.S. Made by American Home Products,
one of the world's largest drug companies, these prescription drugs
worked to lower people's appetite by interfering with the body's
production of serotonin. When first introduced, these diet drugs
seemed to be effective weight loss treatments and were received
with excitement. However, Pondimin, Redux and Fen-Phen
use has been associated with pulmonary hypertension and it is one of the main
risk factors for the disease.
In
1996, sales of Pondimin and Redux totaled well over 20 million
prescriptions. According to company estimates, 4 million people
have used Pondimin and another 2 million have used Redux.
During
the period from March to August 1997, the Mayo clinic in Rochester,
Minnesota observed and reported an association between the use of
Pondimin and/or Redux and valvular heart disease (VHD). Pondimin
and Redux were designed to suppress the appetite by altering brain
levels of serotonin, but both were withdrawn simultaneously from
the market in September of 1997 when they were linked to
the occurrence of serious cardiac valvular disease and primary
pulmonary hypertension.
Under pressure from the FDA, concerned medical authorities and injured
Fen-Phen patients who had filed lawsuits, American Home Products
took the drugs off the market.
A
recent Mayo Clinic study published in the New England Journal of
Medicine suggests that as high as one-third of a patient sampling
of Fen-Phen diet pill users had evidence of heart valve disease.
The study found that there was a high incidence of heart valve disease
in patients taking these diet pills, without any other known reason
for valve disease.
Studies
estimate that treatment with certain appetite suppressant drugs
increases the risk of getting PPH from about one to 28 cases per
million person-years (one person-year represents a patient treated
for one year.)
People
who used one or a combination of these drugs over a longer period
are at greater risk, but cases of PPH have developed in people who
took the drug for as little as two months. New studies by some of
the world's foremost experts on PPH have shown that people who took
diet drugs five years ago are still at risk of developing primary
pulmonary hypertension. New cases of PPH in patients who have used
Redux or Pondimin alone or in combination with other weight-loss
agents are continuing to be diagnosed.
Since
1997 millions of Fen-Phen patients have filed lawsuits against American
Home Products. The vast majority of these claims were for heart
valve disease and have been settled in January and May 2003 as part
of a 4 billion dollar settlement. This settlement did not
affect victims of PPH. So if you have been diagnosed with
PPH and took these diet drugs, you may be entitled to compensation
from the manufacturer.
Read
About Your Legal Rights
If
you or a loved one has PPH
and took Fen-Phen, Pondimin or Redux, you need legal help now.
Click
Here to find a PPH attorney

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